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Using two separate drugs to shed weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err to the side of caution and permit the FDA do its job and demand some investigation be done so the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on the medications. Researchers discovered that participants taking this drug for the year, dropped excess weight within four weeks and have kept the load off throughout the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of multiple active ingredient, which might make them more efficient and safer. Combo-pilling may be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular may be the fact that as of right now there are no long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise blood pressure levels and heartrate, and mustn't be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and heartrate and must not used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. 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